Description

(+)-Biperiden CAS NO 106347-58-4 is the pharmacologically active enantiomer of the anticholinergic agent Biperiden. This high-purity chiral compound is critical for advanced pharmaceutical research and development, particularly in the study of selective receptor interactions. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on neurology and central nervous system disorders.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of enantiomerically pure anticholinergic medications.
• Neurological Research: Used as a reference standard and tool compound in studies targeting muscarinic acetylcholine receptors (mAChRs).
• Pharmacology & Toxicology Studies: Employed in preclinical research to investigate the effects and mechanisms of selective anticholinergic agents.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Process Development: Used in the development and optimization of asymmetric synthesis routes within process chemistry.

Basic Information

Product Name	(+)-Biperiden
CAS No.	106347-58-4
Molecular Formula	C21H29NO
Molecular Weight	311.47 g/mol
Synonyms	(+)-Biperiden; (3R)-1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-piperidin-1-ylpropan-1-ol; Dexbiperiden; (R)-Biperiden; Biperiden enantiomer (+); Dexbiperiden hydrochloride (salt form); Akineton (trade name reference, enantiomerically pure form)
EINECS	Contact for details

Quality Control

Our (+)-Biperiden is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when appropriate.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.