Description

Boc-Beta,β-Dimethyl-D-Cys(Mob)-Oh is a sophisticated, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for medicinal chemists and researchers developing novel therapeutic peptides and peptidomimetics. It is primarily utilized in pharmaceutical R&D for the construction of complex peptide chains where the unique steric and electronic properties of the dimethylated cysteine side chain are required.

Application

• Pharmaceutical Research & Development (R&D): A key intermediate in the solid-phase and solution-phase synthesis of therapeutic peptides targeting various diseases.
• Peptidomimetic Drug Design: Used to introduce constrained, non-natural amino acid residues that enhance metabolic stability and receptor binding affinity of peptide-based drug candidates.
• Chemical Biology Probes: Serves as a specialized building block for creating labeled or modified peptides used in studying protein-protein interactions and enzyme mechanisms.
• API (Active Pharmaceutical Ingredient) Synthesis: Employed in the multi-step synthesis of complex peptide Active Pharmaceutical Ingredients under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	Boc-Beta,β-Dimethyl-D-Cys(Mob)-Oh
CAS No.	106306-57-4
Molecular Formula	C₁₇H₂₅NO₅S
Molecular Weight	355.45 g/mol
Synonyms	(2R)-3-[(4-Methoxybenzyl)sulfanyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-methylpropanoic acid; Boc-D-β,β-dimethylcysteine(4-methoxybenzyl) ether; Boc-D-Cys(βMe,βMe)-OH(Mob); tert-Butyloxycarbonyl-D-β,β-dimethylcysteine(Mob)-OH; N-(tert-Butoxycarbonyl)-3-[(4-methoxybenzyl)thio]-D-β,β-dimethylalanine; Boc-D-β,β-Dimethyl-Cys(Mob)-OH; N-Boc-D-β,β-dimethylcysteine(Mob)
EINECS	Contact for details

Quality Control

Our Boc-Beta,β-Dimethyl-D-Cys(Mob)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.