Description

3-n-Methylparomomycin I is a semi-synthetic derivative of the aminoglycoside antibiotic paromomycin, characterized by a specific methylation pattern that can influence its biological activity and pharmacological profile. This compound is of significant interest in pharmaceutical research and development for exploring novel antibacterial agents and studying structure-activity relationships. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel aminoglycoside antibiotics and derivatives.
• Biochemical Research: Used as a reference standard in studies investigating antibiotic mechanisms of action, resistance, and ribosomal targeting.
• Antimicrobial Development: Acts as a precursor for developing new therapeutic agents targeting bacterial infections, particularly those caused by resistant strains.
• Quality Control & Analytical Standards: Employed as a high-purity certified reference material (CRM) for HPLC, LC-MS, and other analytical methods in QC laboratories.
• Life Science Reagent: Utilized in microbiological and enzymatic assays to study protein synthesis inhibition.

Basic Information

Product Name	3-n-Methylparomomycin I
CAS No.	106288-50-0
Molecular Formula	C24H47N5O14
Molecular Weight	629.66 g/mol
Synonyms	3'-N-Methylparomomycin I; Paromomycin, 3'-N-methyl-; 3'-N-Methylparomomycin; 3'-Methylparomomycin I; Antibiotic U-58820; Antibiotic U58820; U-58820; U58820
EINECS	Contact for details

Quality Control

Our 3-n-Methylparomomycin I is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR, MS), and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under inert atmosphere or in a desiccator for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.