Description

3-(2-Naphthyl)-Dl-Alanine is a synthetic, non-natural amino acid derivative featuring a naphthyl side chain. This structural motif makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel compounds, including peptide-based drugs, enzyme inhibitors, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for non-standard amino acid incorporation.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce hydrophobic, aromatic character into peptide sequences, modifying their biological activity and stability.
• Biochemical Research: Serves as a substrate analog or inhibitor in enzymatic studies to investigate substrate specificity and enzyme mechanisms.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecules with defined stereochemistry.
• Ligand and Catalyst Development: The naphthyl group provides a rigid, bulky framework useful for designing novel chiral ligands and organocatalysts.
• Material Science Research: Potential monomer for creating specialized polymers with unique optical or electronic properties derived from the aromatic system.

Basic Information

Product Name	3-(2-Naphthyl)-Dl-Alanine
CAS No.	106107-92-0
Molecular Formula	C₁₃H₁₃NO₂
Molecular Weight	215.25 g/mol
Synonyms	DL-3-(2-Naphthyl)alanine; 2-Amino-3-(naphthalen-2-yl)propanoic acid (racemic); (±)-2-Amino-3-(2-naphthyl)propionic acid; 3-(2-Naphthyl)alanine; 2-Naphthylalanine; NSC 404058; (RS)-2-Amino-3-(naphthalen-2-yl)propanoic acid; β-(2-Naphthyl)-DL-alanine
EINECS	Contact for details

Quality Control

Our 3-(2-Naphthyl)-Dl-Alanine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (DL)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.