Description

Fasiplon is a high-purity pharmaceutical intermediate and research chemical with significant importance in modern medicinal chemistry. Its primary value lies in its role as a key building block for the synthesis of novel therapeutic agents, particularly within the central nervous system (CNS) sector. This compound is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of advanced drug candidates and active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a key scaffold in the research and development of novel compounds targeting the central nervous system.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional laboratories for pharmacological studies and the development of new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Fasiplon
CAS No.	106100-65-6
Molecular Formula	C15H12N2O2
Molecular Weight	252.27 g/mol
Synonyms	Fasiplon; 7-Bromo-5-(2-pyridinyl)-3H-1,4-benzodiazepin-2(1H)-one; 7-Bromo-5-(pyridin-2-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; ZK-91296; Abecarnil (related analog); Pyridinylbenzodiazepinone derivative; 1,4-Benzodiazepine derivative
EINECS	Contact for details

Quality Control

Our Fasiplon is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our standard grade meets typical research and intermediate specifications, with the capability to supply material compliant with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.