Description

Cyclic Cystathionine CAS NO 105990-93-0 is a specialized cyclic derivative of the sulfur-containing amino acid cystathionine, serving as a crucial intermediate and reference standard in advanced biochemical research. This compound is valued for its role in studying metabolic pathways, particularly those involving sulfur amino acid metabolism and homocysteine regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on developing novel therapeutics and analytical methods for metabolic disorders.

Application

• Pharmaceutical Research & Development: A key intermediate and reference standard in the synthesis and study of novel drug candidates targeting homocysteine-related cardiovascular and neurological conditions.
• Biochemical Pathway Analysis: Used as a critical reagent to investigate and elucidate the transsulfuration pathway and sulfur amino acid metabolism in cellular and enzymatic studies.
• Diagnostic Kit Manufacturing: Serves as a high-purity calibrant and control substance in the production of diagnostic assays for measuring homocysteine and related metabolites in clinical samples.
• Academic & Life Science Research: An essential tool for fundamental research in biochemistry, molecular biology, and nutrition science to understand metabolic regulation and disease mechanisms.
• Metabolomics & Biomarker Discovery: Employed as a known standard in mass spectrometry and chromatography-based metabolomic profiling to identify and quantify sulfur metabolites.
• Enzyme Inhibition Studies: Utilized to study the activity and inhibition of key enzymes like cystathionine β-synthase (CBS) and cystathionine γ-lyase (CGL).

Basic Information

Product Name	Cyclic Cystathionine
CAS No.	105990-93-0
Molecular Formula	C7H14N2O4S
Molecular Weight	222.26 g/mol
Synonyms	L-Cystathionine, cyclic; Cyclic L-Cystathionine; (S)-2-Amino-4-((S)-2-amino-2-carboxyethyl)thiazolidine-4-carboxylic acid; 2-Amino-4-(2-amino-2-carboxyethyl)thiazolidine-4-carboxylic acid; Thiazolidine derivative of cystathionine; Cyclic thioether of cystathionine; Homocysteine-cysteine cyclic disulfide analog
EINECS	Contact for details

Quality Control

Our Cyclic Cystathionine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and chiral purity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data and full spectral characterization are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.