Description

3,5-Difluoro-4-Methoxybenzylamine is a high-purity, functionalized benzylamine derivative characterized by its difluoro and methoxy substituents, offering unique electronic and steric properties for advanced synthesis. This compound serves as a critical pharmaceutical intermediate and versatile building block in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production in medicinal chemistry, material science, and fine chemical synthesis, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into the design of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for academic and industrial R&D in organic and medicinal chemistry for constructing complex molecular frameworks.
• Fluorinated Compound Library: Used in combinatorial chemistry and high-throughput screening to create libraries of fluorinated compounds for biological evaluation.

Basic Information

Product Name	3,5-Difluoro-4-Methoxybenzylamine
CAS No.	105969-16-2
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	4-Methoxy-3,5-difluorobenzylamine; (3,5-Difluoro-4-methoxyphenyl)methanamine; Benzenemethanamine, 3,5-difluoro-4-methoxy-; 3,5-Difluoro-4-methoxybenzylamine; 3,5-Difluoro-p-anisylamine; 3,5-Difluoro-4-methoxybenzenemethanamine; 105969-16-2
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methoxybenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, prolonged exposure to light, air, or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.