Description

Clinafloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic known for its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including multi-drug resistant strains. Its primary value lies in its enhanced efficacy, particularly in research settings for studying novel antibacterial mechanisms and overcoming resistance. This compound is essential for pharmaceutical R&D laboratories, academic institutions, and manufacturers focused on developing advanced antimicrobial agents and reference standards.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antibacterial therapies.
• Microbiological Studies: Used in in vitro assays to study bacterial susceptibility, resistance patterns, and the pharmacodynamics of fluoroquinolones.
• Analytical Chemistry: Employed as a high-purity standard for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Preclinical Investigations: Utilized in animal model studies to evaluate the efficacy, pharmacokinetics, and safety profile of advanced antibiotic candidates.

Basic Information

Product Name	Clinafloxacin
CAS No.	105956-97-6
Molecular Formula	C17H17ClF3N3O3
Molecular Weight	415.78 g/mol
Synonyms	Clinafloxacin; PD-127391; AM-1091; (R,S)-7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3S,5R)-3-amino-5-methyl-1-piperazinyl-4-oxo-3-quinolinecarboxylic acid (mixture with other isomers); CI-960; PD127391
EINECS	Contact for details

Quality Control

Our Clinafloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and HPLC, assay determination, and control of related substances and residual solvents, to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.