Description

Arg-His-Phe is a high-purity synthetic tripeptide composed of the amino acids arginine, histidine, and phenylalanine. This compound is a critical building block in pharmaceutical research and development, particularly for studying peptide structure-activity relationships and metabolic pathways. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, high-quality peptide substrates for drug discovery and biochemical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor binding assays, and metabolic pathway investigations.
• Proteomics & Peptide Mapping: Acts as a reference compound in mass spectrometry for protein sequencing and identification.
• Cell Culture & Media Supplement: Employed in specialized cell culture media formulations to study amino acid uptake and cellular metabolism.
• Cosmetic Peptide Synthesis: A potential precursor in the development of bioactive peptides for advanced skincare formulations.
• Academic & Contract Research: Essential for universities and CROs conducting fundamental research in biochemistry, pharmacology, and medicinal chemistry.

Basic Information

Product Name	Arg-His-Phe
CAS No.	105931-68-8
Molecular Formula	C23H34N10O5
Molecular Weight	530.59 g/mol
Synonyms	Arginyl-Histidyl-Phenylalanine; Arg-His-Phe-OH; L-Arginyl-L-histidyl-L-phenylalanine; RHF; H-Arg-His-Phe-OH; Tripeptide RHF; UNII-6G8V8H8V8P; AHX-510
EINECS	Contact for details

Quality Control

Our Arg-His-Phe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.