Description

L-Norleucine, 2-Methyl- (9Ci) is a non-proteinogenic amino acid derivative, specifically a methylated analog of L-norleucine. This compound is valued for its role as a specialized building block in peptide synthesis and as a chiral intermediate in advanced pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce structural modifications and study structure-activity relationships (SAR).
• Biochemical Research: Acts as a metabolic probe or an analog in enzymatic studies and metabolic pathway analysis.
• Fine Chemical Production: Employed as a precursor for the manufacture of more complex, high-value specialty chemicals and catalysts.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	L-Norleucine, 2-Methyl- (9Ci)
CAS No.	105815-96-1
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(2S)-2-Amino-2-methylhexanoic acid; L-2-Amino-2-methylcaproic acid; L-2-Methylnorleucine; (S)-2-Amino-2-methylhexanoic acid; 2-Methyl-L-norleucine; L-α-Methylnorleucine; 2-Amino-2-methylhexanoic acid, L-; Norleucine, 2-methyl-, L-
EINECS	Contact for details

Quality Control

Our L-Norleucine, 2-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for research and synthesis applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.