Description

4,6-Dichloro-5-Fluoro-2-Methylpyrimidine is a high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. It is primarily sought after by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides and fungicides containing fluorinated pyrimidine structures.
• Material Science: Serves as a precursor for functionalized polymers and liquid crystals.
• Chemical Synthesis: Versatile substrate for nucleophilic substitution reactions to introduce diverse functional groups at the chloro positions.
• Antiviral Drug Development: Integral in the research and production of antiviral compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4,6-Dichloro-5-Fluoro-2-Methylpyrimidine
CAS No.	105806-13-1
Molecular Formula	C5H3Cl2FN2
Molecular Weight	180.99 g/mol
Synonyms	5-Fluoro-4,6-dichloro-2-methylpyrimidine; 2-Methyl-4,6-dichloro-5-fluoropyrimidine; 4,6-Dichloro-5-fluoro-2-methyl-1,3-diazine; 4,6-Dichloro-5-fluoro-2-methyl-pyrimidine; DC-FMP
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-Fluoro-2-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.