Description

5-Bromo-6-Chloro-2-Methylpyrimidin-4-Ol is a high-purity halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which makes it an essential intermediate for constructing complex molecules with specific biological activities. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging its halogenated pyrimidine core.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in electronic materials or liquid crystals.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	5-Bromo-6-Chloro-2-Methylpyrimidin-4-Ol
CAS No.	105806-11-9
Molecular Formula	C5H4BrClN2O
Molecular Weight	223.46 g/mol
Synonyms	5-Bromo-6-chloro-2-methyl-4-pyrimidinol; 4-Hydroxy-5-bromo-6-chloro-2-methylpyrimidine; 5-Bromo-6-chloro-2-methyl-4(1H)-pyrimidinone; 5-Bromo-6-chloro-2-methylpyrimidin-4(3H)-one; 2-Methyl-5-bromo-6-chloropyrimidin-4-ol; 5-Bromo-6-chloro-2-methyl-4-hydroxypyrimidine; 105806-11-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloro-2-Methylpyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.