Description

Ac-Met-Glu-Oh CAS NO 105777-14-8 is a high-purity, custom synthetic peptide derivative, specifically the acetylated form of the tripeptide methionylglutamylglycine. This compound serves as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical R&D laboratories engaged in peptide synthesis, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel peptide-based drugs and bioactive compounds.
• Biochemical Research: Used in enzymatic studies, substrate specificity assays, and investigations into peptide metabolism and degradation pathways.
• Proteomics & Mass Spectrometry: Serves as a calibrant or standard in analytical techniques like HPLC-MS for method development and quantification.
• Academic Research: A valuable tool for universities and research institutes studying protein chemistry, peptide structure-activity relationships, and molecular biology.
• Custom Peptide Synthesis: Acts as a specialized starting material or fragment for contract research organizations (CROs) and CDMOs producing custom peptides for clients.

Basic Information

Product Name	Ac-Met-Glu-Oh
CAS No.	105777-14-8
Molecular Formula	C15H25N3O7S
Molecular Weight	391.44 g/mol
Synonyms	Ac-Met-Glu-OH; Acetyl-Methionyl-Glutamyl-Glycine; N-Acetyl-Met-Glu-Gly-OH; Ac-Met-Glu-Gly; Ac-MEG-OH; N-Acetyl-L-methionyl-L-glutamylglycine; L-Methionine, N-acetyl-, 1-(N-L-glutamyl)glycine ester; (2S)-2-Acetamido-4-(methylsulfanyl)butanoyl-L-glutamylglycine
EINECS	Contact for details

Quality Control

Every batch of Ac-Met-Glu-Oh is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.