Description

4,5-Dichloro-2,6-Dimethylpyrimidine is a versatile halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chlorinated pyrimidine motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the dichloropyrimidine core is a functional component.
• Material Science Research: Serves as a precursor for creating functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	4,5-Dichloro-2,6-Dimethylpyrimidine
CAS No.	105742-66-3
Molecular Formula	C6H6Cl2N2
Molecular Weight	177.03 g/mol
Synonyms	2,6-Dimethyl-4,5-dichloropyrimidine; 4,5-Dichloro-2,6-dimethyl-1,3-diazine; 4,5-Dichloro-2,6-dimethyl-pyrimidine; Pyrimidine, 4,5-dichloro-2,6-dimethyl-; 105742-66-3; 4,5-Dichloro-2,6-dimethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-2,6-Dimethylpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.