Description

3-Azido-L-Alanine is a non-proteinogenic amino acid derivative featuring a reactive azido group, making it a valuable click chemistry reagent and a versatile building block in chemical synthesis. Its primary value lies in enabling bioorthogonal conjugation strategies, particularly in the development of novel bioconjugates, probes, and pharmaceutical intermediates. This compound is essential for researchers and manufacturers in pharmaceutical R&D, proteomics, and advanced materials science, where precise molecular tagging and functionalization are required.

Application

• Click Chemistry Reagent: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for labeling biomolecules.
• Peptide & Protein Modification: Serves as a metabolic precursor or a synthetic handle for site-specific incorporation of azide groups into peptides and proteins.
• Bioconjugate Synthesis: A key intermediate for creating antibody-drug conjugates (ADCs), peptide-drug conjugates, and other targeted therapeutics.
• Chemical Biology Probes: Enables the development of activity-based probes and imaging agents for studying biological processes.
• Materials Science: Used in the surface functionalization of polymers and nanoparticles to introduce bio-active interfaces.
• Pharmaceutical Intermediate: Employed in the synthesis of more complex molecules with potential therapeutic activity.

Basic Information

Product Name	3-Azido-L-Alanine
CAS No.	105661-40-3
Molecular Formula	C3H6N4O2
Molecular Weight	130.10 g/mol
Synonyms	L-3-Azidoalanine; (S)-2-Amino-3-azidopropanoic acid; Azido-L-alanine; 3-Azidoalanine; 3-Azido-L-α-alanine; β-Azido-L-alanine; L-β-Azidoalanine; AzAla
EINECS	Contact for details

Quality Control

Our 3-Azido-L-Alanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.