Description

Dermorphin, Ala(4)- CAS NO 105413-88-5 is a synthetic peptide analog of the potent natural opioid heptapeptide dermorphin. This compound is of significant interest for its high affinity and selectivity for the μ-opioid receptor, making it a valuable research tool in neuropharmacology and pain management studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel analgesic pathways and studying opioid receptor mechanisms.

Application

• Neuroscience Research: Used as a selective μ-opioid receptor agonist to study receptor binding, signal transduction, and neural pathways in vitro and in vivo.
• Analgesic Drug Development: Serves as a reference standard and lead compound in the discovery and screening of new, potent pain-relief medications with potentially improved safety profiles.
• Biochemical Assays: Employed in competitive binding assays and functional tests to evaluate the potency and efficacy of other opioid compounds.
• Pharmacology Studies: Facilitates research into tolerance, dependence, and the side effects associated with opioid receptor activation.
• Reference Standard: Used for the calibration of analytical equipment (HPLC, MS) and for quality control in peptide synthesis and characterization.

Basic Information

Product Name	Dermorphin, Ala(4)-
CAS No.	105413-88-5
Molecular Formula	C₄₀H₅₈N₁₀O₁₀
Molecular Weight	826.96 g/mol
Synonyms	[D-Ala², Ala⁴]-Dermorphin; H-Tyr-D-Ala-Phe-Ala-Tyr-Pro-Ser-NH₂; Ala⁴-Dermorphin; Dermorphin (1-7) amide, [D-Ala²,Ala⁴]-; Dermorphin analog; μ-opioid receptor agonist peptide; Tyr-D-Ala-Phe-Ala-Tyr-Pro-Ser-NH₂
EINECS	Contact for details

Quality Control

Our Dermorphin, Ala(4)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.