Description

Ethyl 6-Nitropyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity, heterocyclic organic compound characterized by its pyrazolopyrimidine core functionalized with nitro and ester groups. This specialized chemical building block is critical for advanced research and development in medicinal chemistry, enabling the synthesis of novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients for crop protection products.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic systems due to its reactive nitro and ester functionalities.
• Biochemical Probe Development: Utilized in the creation of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	Ethyl 6-Nitropyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	105411-95-8
Molecular Formula	C9H8N4O4
Molecular Weight	236.19 g/mol
Synonyms	Ethyl 6-nitropyrazolo[1,5-a]pyrimidine-3-carboxylate; 6-Nitro-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 6-nitro-, ethyl ester; Ethyl 6-nitro-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylate; 105411-95-8; ENPPC
EINECS	Contact for details

Quality Control

Our Ethyl 6-Nitropyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.