Description

1,2-Dimyristoyl-Sn-Glycero-3-Phospho-L-Serine Sodium Salt is a high-purity, synthetic phospholipid essential for constructing biomimetic membranes and advanced drug delivery systems. Its primary value lies in its role as a key component of liposomes and lipid nanoparticles (LNPs), enabling the encapsulation and targeted delivery of sensitive active pharmaceutical ingredients (APIs). This product is critically needed by pharmaceutical R&D teams, formulation scientists, and manufacturers in the life sciences sector for applications in vaccine development, mRNA therapeutics, and cancer treatment research.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A critical anionic lipid component for creating stable, functional liposomal and LNP structures for drug and gene delivery.
• mRNA Vaccine & Therapeutic Carrier Systems: Used in the lipid bilayer to encapsulate and protect mRNA, enhancing cellular uptake and transfection efficiency.
• Biomimetic Membrane Research: Serves as a model phospholipid for studying cell membrane properties, protein-lipid interactions, and membrane fusion processes.
• Drug Delivery Targeting: The anionic charge of the phosphatidylserine headgroup can be utilized for passive targeting or further functionalization for active targeting strategies.
• Diagnostic Reagent Development: Employed in the formulation of contrast agents and diagnostic probes for imaging applications.
• Cosmetic & Dermal Formulations: Used in high-end cosmetic products as a skin-identical lipid to improve skin barrier function and delivery of active compounds.

Basic Information

Product Name	1,2-Dimyristoyl-Sn-Glycero-3-Phospho-L-Serine Sodium Salt
CAS No.	105405-50-3
Molecular Formula	C34H65NNaO10P
Molecular Weight	701.84 g/mol
Synonyms	DMPS (Na Salt); 1,2-Dimyristoyl-sn-glycero-3-phosphoserine sodium salt; 14:0 PS Sodium Salt; Phosphatidylserine (14:0/14:0) Sodium Salt; L-α-Phosphatidylserine, dimyristoyl, sodium salt; Sodium 1,2-ditetradecanoyl-sn-glycero-3-phospho-L-serine; PS(14:0/14:0) Na; DMPS-Na
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phospho-L-Serine Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol; forms dispersions in water
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.