Description

4-(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)benzonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proprietary drug candidates, especially those targeting kinase inhibition and other enzyme-related pathways.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of focused compound libraries.
• Biochemical Research: Serves as a reference standard or a probe molecule in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry research.

Basic Information

Product Name	4-(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)benzonitrile
CAS No.	105365-76-2
Molecular Formula	C14H12N4O
Molecular Weight	252.27 g/mol
Synonyms	4-[(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino]benzonitrile; 4-(7-Hydroxy-5,6,7,8-tetrahydrocyclopenta[d]pyrimidin-4-ylamino)benzonitrile; 4-[(7-Hydroxy-5,6,7,8-tetrahydrocyclopenta[d]pyrimidin-4-yl)amino]benzonitrile; 4-Amino-7-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine benzonitrile derivative; CPDPA Benzonitrile; CAS 105365-76-2
EINECS	Contact for details

Quality Control

Our production of 4-(7-Hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)benzonitrile adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.