Description

[4-(4-Amino-7-Hydroxy-6-Methoxy-2-Quinazolinyl)-1-Piperazinyl](Tetrahydro-2-Furanyl)Methanone is a sophisticated heterocyclic organic compound featuring a quinazoline core linked to a piperazine and a tetrahydrofuran moiety. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and other therapeutic areas.
• Research & Development: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Acts as a key precursor for the development of complex molecules with potential biological activity.
• Biochemical Research: May be employed in biochemical assays and as a tool compound for probing specific biological pathways.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	[4-(4-Amino-7-Hydroxy-6-Methoxy-2-Quinazolinyl)-1-Piperazinyl](Tetrahydro-2-Furanyl)Methanone
CAS No.	105356-90-9
Molecular Formula	C₁₈H₂₃N₅O₄
Molecular Weight	373.41 g/mol
Synonyms	4-(4-Amino-7-hydroxy-6-methoxy-2-quinazolinyl)-1-piperazinyl(tetrahydro-2-furanyl)methanone; (Tetrahydrofuran-2-yl)-[4-(4-amino-7-hydroxy-6-methoxyquinazolin-2-yl)piperazin-1-yl]methanone; 105356-90-9; Quinazoline-piperazine-tetrahydrofuran methanone derivative; 2-[4-(Oxolane-2-carbonyl)piperazin-1-yl]-6-methoxy-7-hydroxyquinazolin-4-amine
EINECS	Contact for details

Quality Control

Our [4-(4-Amino-7-Hydroxy-6-Methoxy-2-Quinazolinyl)-1-Piperazinyl](Tetrahydro-2-Furanyl)Methanone is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.