Description

[4-(4-Amino-6-Hydroxy-7-Methoxy-2-Quinazolinyl)-1-Piperazinyl](Tetrahydro-2-Furanyl)Methanone is a sophisticated quinazoline derivative building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for developing novel pharmaceutical agents, particularly in research areas targeting specific enzyme inhibition. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating new active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Biochemical Research: Used as a reference standard or building block in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex heterocyclic frameworks with potential biological activity.
• API Development: Integral in the research and process development stages for new Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences sector.

Basic Information

Product Name	[4-(4-Amino-6-Hydroxy-7-Methoxy-2-Quinazolinyl)-1-Piperazinyl](Tetrahydro-2-Furanyl)Methanone
CAS No.	105356-89-6
Molecular Formula	C₁₈H₂₃N₅O₄
Molecular Weight	373.41 g/mol
Synonyms	4-(4-Amino-6-hydroxy-7-methoxyquinazolin-2-yl)piperazin-1-yl(tetrahydrofuran-2-yl)methanone; (Tetrahydro-2-furanyl){4-[4-amino-6-hydroxy-7-methoxy-2-quinazolinyl]-1-piperazinyl}methanone; 105356-89-6; 4-Amino-6-hydroxy-7-methoxy-2-[4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl]quinazoline; Quinazoline piperazine furanone derivative
EINECS	Contact for details

Quality Control

Our [4-(4-Amino-6-Hydroxy-7-Methoxy-2-Quinazolinyl)-1-Piperazinyl](Tetrahydro-2-Furanyl)Methanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.