Description

4-Morpholino-3-(trifluoromethyl)benzenamine is a high-value aromatic amine derivative featuring both morpholine and trifluoromethyl functional groups. This unique structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in synthetic organic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in catalytic systems for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of specialty polymers, dyes, and organic electronic materials due to its electron-donating morpholine moiety and fluorine content.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	4-Morpholino-3-(trifluoromethyl)benzenamine
CAS No.	105316-06-1
Molecular Formula	C11H13F3N2O
Molecular Weight	246.23 g/mol
Synonyms	3-(Trifluoromethyl)-4-morpholinoaniline; 4-Amino-2-(trifluoromethyl)phenyl morpholino ether; Benzenamine, 4-morpholino-3-(trifluoromethyl)-; 3-Trifluoromethyl-4-morpholinoaniline; 4-Morpholino-3-trifluoromethylaniline; 2-(Trifluoromethyl)-4-aminophenyl morpholino ether; 4-Morpholino-α,α,α-trifluoro-m-toluidine
EINECS	Contact for details

Quality Control

Every batch of 4-Morpholino-3-(trifluoromethyl)benzenamine is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles to ensure compliance with your project specifications. Our quality commitment supports applications requiring cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.