Description

Lysinethiol CAS NO 105290-01-5 is a specialized amino acid derivative that serves as a critical building block in advanced chemical synthesis. This compound is valued for its unique thiol functional group, which enables its use as a key intermediate in the production of pharmaceuticals and biochemical research reagents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting various disease pathways.
• Bioconjugation & Protein Engineering: Used in the site-specific modification of proteins, peptides, and antibodies due to its reactive thiol group, enabling the creation of targeted drug conjugates and diagnostic tools.
• Biochemical Research: Serves as a valuable reagent in life science research for studying enzyme mechanisms, protein structure-function relationships, and cellular signaling processes.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to introduce thiol-containing side chains, expanding the chemical diversity of synthetic peptide libraries.
• Cross-linking Agent: Acts as a heterobifunctional cross-linker for creating stable covalent bonds between biomolecules or between biomolecules and surfaces in bioconjugation chemistry.
• Precursor for Chelating Agents: Can be utilized as a starting material for synthesizing specialized chelating ligands used in metal catalysis or medical imaging.

Basic Information

Product Name	Lysinethiol
CAS No.	105290-01-5
Molecular Formula	C6H14N2O2S
Molecular Weight	178.25 g/mol
Synonyms	S-(2-Aminoethyl)-L-cysteine; L-Lysinethiol; H-Lys(Cys)-OH; (2S)-2-Amino-6-[(2-amino-2-carboxyethyl)sulfanyl]hexanoic acid; Lysine thiol derivative; Aminoethylcysteine; Thiolysine; L-2-Amino-6-[(2-amino-2-carboxyethyl)thio]hexanoic acid
EINECS	Contact for details

Quality Control

Our Lysinethiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation and specific tests for related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a freezer (-20°C). Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.