Description

H-Tyr-Gly-Phe-Gly-Gly-Oh is a synthetic pentapeptide with the sequence Tyrosine-Glycine-Phenylalanine-Glycine-Glycine. This compound is a valuable building block in peptide synthesis and biochemical research, offering a defined sequence for studying structure-activity relationships. It is primarily utilized by research institutions and pharmaceutical developers focused on neurochemistry, peptide hormone analogs, and advanced drug discovery platforms.

Application

• Biochemical Research: Used as a standard or intermediate in studying peptide conformation, receptor binding, and enzymatic cleavage.
• Pharmaceutical R&D: Serves as a key precursor or model compound in the development of novel therapeutic peptides targeting neurological pathways.
• Academic Studies: Employed in university laboratories for teaching advanced peptide chemistry and molecular biology techniques.
• Peptide Library Synthesis: Acts as a core structure for generating focused libraries to screen for biological activity in high-throughput assays.
• Enzyme Substrate Studies: Utilized to investigate the specificity and kinetics of proteases and other peptide-processing enzymes.

Basic Information

Product Name	H-Tyr-Gly-Phe-Gly-Gly-Oh
CAS No.	105250-85-9
Molecular Formula	C25H30N6O7
Molecular Weight	526.54 g/mol
Synonyms	Tyr-Gly-Phe-Gly-Gly; YGFGG; H-Tyr-Gly-Phe-Gly-Gly-OH; L-Tyrosylglycyl-L-phenylalanylglycylglycine; Pentapeptide YGFGG; Glycylglycyl-L-phenylalanylglycyl-L-tyrosine; 2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid
EINECS	Contact for details

Quality Control

Our H-Tyr-Gly-Phe-Gly-Gly-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry. Certificates of Analysis (COA) detailing purity, residual solvents, and other critical parameters are available upon request to ensure compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.