Description

H-Arg-Gly-Oh Hcl is a high-purity, protected dipeptide derivative used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over amino acid sequence and side-chain functionality. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides, diagnostic agents, and biochemical research reagents.

Application

• Pharmaceutical Intermediate: A key raw material in the solid-phase and solution-phase synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, proteomics research, and metabolic pathway investigations.
• Peptide Library Construction: Serves as a fundamental building block for creating combinatorial peptide libraries used in drug discovery and high-throughput screening.
• Cosmetic Peptide Synthesis: Incorporated into the manufacture of bioactive peptides for advanced skincare and cosmetic formulations.
• Diagnostic Reagent Production: Employed in the development of peptide-conjugated markers, antibodies, and assay components for clinical diagnostics.

Basic Information

Product Name	H-Arg-Gly-Oh Hcl
CAS No.	105241-88-1
Molecular Formula	C8H18N6O3 • HCl
Molecular Weight	282.73 g/mol (Free base: 246.27)
Synonyms	H-Arg-Gly-OH hydrochloride; Nα-Boc-NG-Pbf-L-arginyl-glycine; Boc-Arg(Pbf)-Gly-OH; Boc-L-Arg(Pbf)-Gly-OH; (2S)-5-[[(2,2,4,6,7-Pentamethyl-2,3-dihydro-1-benzofuran-5-yl)sulfonyl]amino]-2-[[2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]acetyl]amino]pentanoic acid; Boc-Arg(Pbf)-Glycine; Nα-Boc-Nω-Pbf-L-arginyl-glycine
EINECS	Contact for details

Quality Control

Our H-Arg-Gly-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by mass spectrometry and IR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere (nitrogen or argon) when not in use to prevent degradation and maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Specific Rotation	-15° to -25° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.