Description

3-Amino-4-Iodobenzotrifluoride is a high-value, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and electron-withdrawing trifluoromethyl and iodo substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials, host materials, and other functional components in display and lighting technologies.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create complex biaryl and conjugated systems.
• Dye & Pigment Manufacturing: Intermediate for producing specialized azo dyes and high-performance pigments with improved lightfastness and color properties.
• Polymer Modification: Used to introduce fluorinated aromatic units into polymer backbones to alter thermal stability, chemical resistance, and optical characteristics.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	3-Amino-4-Iodobenzotrifluoride
CAS No.	105202-02-6
Molecular Formula	C7H5F3IN
Molecular Weight	287.02 g/mol
Synonyms	4-Iodo-3-aminobenzotrifluoride; 3-Amino-α,α,α-trifluoro-4-iodotoluene; 2-Iodo-5-(trifluoromethyl)aniline; 1-Amino-2-iodo-5-(trifluoromethyl)benzene; 5-(Trifluoromethyl)-2-iodoaniline; 3-Amino-4-iodobenzotrifluoride; 3-Amino-4-iodo-α,α,α-trifluorotoluene; Benzenamine, 2-iodo-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Iodobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.