Description

5-Pyrimidinecarboxaldehyde, 4-Amino-1,2-Dihydro-2-Thioxo- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new drug candidates, agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that target specific biochemical pathways.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science: Acts as a building block for creating functionalized heterocyclic polymers or ligands for metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for synthetic methodology development and exploring new chemical spaces in university and CRO laboratories.

Basic Information

Product Name	5-Pyrimidinecarboxaldehyde, 4-Amino-1,2-Dihydro-2-Thioxo- (9Ci)
CAS No.	105161-35-1
Molecular Formula	C5H5N3OS
Molecular Weight	155.18 g/mol
Synonyms	4-Amino-2-mercapto-5-pyrimidinecarboxaldehyde; 4-Amino-2-thioxo-1,2-dihydro-5-pyrimidinecarboxaldehyde; 4-Amino-2-mercaptopyrimidine-5-carboxaldehyde; 5-Formyl-4-amino-2-mercaptopyrimidine; 4-Amino-2-thioxo-1,2-dihydropyrimidine-5-carbaldehyde; 4-Amino-2-sulfanylidene-1H-pyrimidine-5-carbaldehyde; 4-Amino-2-thioxo-1,2-dihydro-pyrimidine-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxaldehyde, 4-Amino-1,2-Dihydro-2-Thioxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.