Description

Neurotensin, Ser(7)- CAS NO 104969-72-4 is a synthetic peptide analog of the endogenous neuropeptide neurotensin, specifically modified at the seventh position with a serine residue. This modification is significant for research into receptor binding affinity, selectivity, and metabolic stability, making it a valuable tool for pharmacological and biochemical studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neuroscience, gastrointestinal physiology, and cancer research.

Application

• Neuroscience Research: Investigation of neurotensin receptor (NTS1 and NTS2) signaling, neuronal excitability, and dopaminergic pathways.
• Pharmacological Studies: Used as a reference standard or active agent in assays to study agonist/antagonist activity and structure-activity relationships (SAR).
• Biochemical Analysis: Serves as a substrate or ligand in enzyme-linked immunosorbent assays (ELISA), radioimmunoassays (RIA), and receptor binding studies.
• Drug Discovery: A key intermediate or tool compound in the development of novel therapeutics targeting neurotensin receptors for conditions like schizophrenia, pain, and cancer.
• Academic Research: Fundamental studies in universities and institutes exploring the role of neurotensin in central and peripheral nervous system function.

Basic Information

Item	Detail
Product Name	Neurotensin, Ser(7)-
CAS No.	104969-72-4
Molecular Formula	C₇₈H₁₂₂N₂₄O₂₂
Molecular Weight	1750.0 g/mol (approx.)
Synonyms	Ser(7)-Neurotensin; [Ser7]-Neurotensin; Neurotensin (7-13), Ser(7)-; pGlu-Leu-Tyr-Glu-Asn-Lys-Ser-Arg-Arg-Pro-Tyr-Ile-Leu-OH; Neurotensin fragment 7-13, Ser7-substituted; NT (7-13), Ser7-
EINECS	Contact for details

Quality Control

Our Neurotensin, Ser(7)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.