Description

Ethyl 5-Chloro-1-(Pyrimidin-2-Yl)-1H-Pyrazole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture that enables targeted drug development. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Serves as a crucial building block for developing new-generation pesticides and herbicides with specific modes of action.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new heterocyclic chemistry and creating compound libraries for screening.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the final chemical steps for producing specific, high-value APIs under GMP conditions.
• Material Science: Investigated for potential use in creating specialty polymers or organic electronic materials due to its conjugated system.

Basic Information

Product Name	Ethyl 5-Chloro-1-(Pyrimidin-2-Yl)-1H-Pyrazole-4-Carboxylate
CAS No.	104909-40-2
Molecular Formula	C10H9ClN4O2
Molecular Weight	252.66 g/mol
Synonyms	5-Chloro-1-(2-pyrimidinyl)-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 5-chloro-1-pyrimidin-2-yl-1H-pyrazole-4-carboxylate; 1H-Pyrazole-4-carboxylic acid, 5-chloro-1-(2-pyrimidinyl)-, ethyl ester; 104909-40-2; UNII-8V3F8J8V6R; 8V3F8J8V6R; SCHEMBL218062; BCP31863
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-1-(Pyrimidin-2-Yl)-1H-Pyrazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.