Description

Boc-Dl-1-Naphthylalanine is a protected amino acid derivative featuring a bulky naphthyl side chain, essential for advanced peptide synthesis and medicinal chemistry research. This compound is a critical chiral building block for introducing structural complexity and modulating the physicochemical properties of target molecules. It is primarily utilized by pharmaceutical R&D teams, agrochemical researchers, and academic laboratories focused on developing novel bioactive peptides and peptidomimetics.

Application

• Pharmaceutical Intermediates: Serves as a key chiral synthon in the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) and solution-phase methods to incorporate a hydrophobic, aromatic amino acid analog into peptide chains.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the impact of bulky aromatic groups on binding affinity and metabolic stability.
• Agrochemical Development: Acts as a building block for synthesizing peptide-based or amino acid-derived active ingredients for crop protection.
• Bioconjugation & Probe Design: Useful for creating fluorescent or affinity probes where the naphthyl group can serve as a hydrophobic tag or a spectroscopic handle.
• Academic & Institutional Research: A valuable reagent for graduate-level and post-doctoral research in organic synthesis, peptide chemistry, and chemical biology.

Basic Information

Product Name	Boc-Dl-1-Naphthylalanine
CAS No.	104882-22-6
Molecular Formula	C₁₈H₂₁NO₄
Molecular Weight	315.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-DL-1-naphthylalanine; Boc-DL-1-Nal-OH; Boc-1-Naphthylalanine; tert-Butyloxycarbonyl-DL-1-naphthylalanine; N-Boc-DL-1-naphthylalanine; (RS)-2-((tert-Butoxycarbonyl)amino)-3-(naphthalen-1-yl)propanoic acid; DL-N-Boc-1-naphthylalanine; 1-Naphthylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, DL-
EINECS	Contact for details

Quality Control

Our Boc-Dl-1-Naphthylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic mixture)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.