Description

Mth-Dl-Norleucine CAS NO 104809-14-5 is a synthetic, non-proteinogenic amino acid derivative, serving as a crucial chiral building block and biochemical research tool. Its value lies in its structural similarity to natural amino acids, allowing it to act as a metabolic probe or an isosteric replacement in peptide synthesis to modulate stability and activity. This compound is essential for researchers and manufacturers in pharmaceutical development, peptide chemistry, and academic research focused on enzyme mechanisms and metabolic pathways.

Application

• Pharmaceutical Intermediates: Used as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and peptidomimetics.
• Biochemical Research: Serves as a metabolic inhibitor or a labeled analog in studies of amino acid transport, enzyme kinetics, and protein biosynthesis.
• Peptide Modification: Incorporated into peptide chains to enhance proteolytic stability, alter hydrophobicity, or study structure-activity relationships (SAR).
• Standards and Reference Materials: Utilized as a high-purity analytical standard for chromatography (HPLC, GC) and mass spectrometry in quality control laboratories.
• Agrochemical Research: Investigated as a component in the design of novel herbicides or plant growth regulators based on amino acid antimetabolites.
• Cosmetic Peptides: Potential use in the synthesis of bioactive peptides for cosmetic applications targeting skin repair and anti-aging.

Basic Information

Item	Detail
Product Name	Mth-Dl-Norleucine
CAS No.	104809-14-5
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	2-Aminohexanoic acid, DL-2-Aminocaproic acid, DL-Norleucine, (±)-2-Aminohexanoic acid, H-DL-Nle-OH, DL-α-Aminocaproic acid, 2-Azaniumylhexanoate
EINECS	Contact for details

Quality Control

Our Mth-Dl-Norleucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support compliance with various pharmacopeial and research-grade specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Contact for specific ratio)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.