Description

4-Chloro-6-Piperidin-1-Yl-Pyrimidin-2-Ylamine is a high-purity pyrimidine derivative, a crucial building block in advanced organic synthesis. Its molecular structure makes it a versatile intermediate for constructing complex molecules with specific biological activities. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its heterocyclic core.
• Material Science: Serves as a building block for creating specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for constructing complex pyrimidine-based libraries for screening.
• Bioconjugate Chemistry: The reactive chloro and amine groups allow for its use in creating targeted molecular probes and conjugates.

Basic Information

Product Name	4-Chloro-6-Piperidin-1-Yl-Pyrimidin-2-Ylamine
CAS No.	104637-64-1
Molecular Formula	C9H14ClN5
Molecular Weight	227.69 g/mol
Synonyms	2-Amino-4-chloro-6-(1-piperidinyl)pyrimidine; 4-Chloro-6-(piperidin-1-yl)pyrimidin-2-amine; 4-Chloro-6-piperidin-1-ylpyrimidin-2-ylamine; 2-Pyrimidinamine, 4-chloro-6-(1-piperidinyl)-; 4-Chloro-6-piperidin-1-yl-2-pyrimidinamine; 104637-64-1; 4-Chloro-6-(1-piperazinyl)-2-pyrimidinamine (common mis-assignment check); 6-Piperidin-1-yl-4-chloropyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Piperidin-1-Yl-Pyrimidin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.