Description

(2R,3S)-2-Amino-3-Hydroxy-Pentanoic Acid CAS NO 104531-21-7 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry. This compound is a critical chiral building block in the synthesis of complex pharmaceuticals and bioactive molecules, where its defined configuration is essential for biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and antibiotic drug candidates.
• Peptide Synthesis: Used as a specialized amino acid residue in solid-phase and solution-phase peptide synthesis to introduce specific structural and functional properties.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway research, and as a precursor for labeled compounds.
• Asymmetric Catalysis: Employed as a chiral ligand or auxiliary in asymmetric synthesis to induce stereoselectivity in chemical transformations.
• Agrochemical Development: A potential intermediate in the research and development of novel, stereospecific pesticides and herbicides.

Basic Information

Product Name	(2R,3S)-2-Amino-3-Hydroxy-Pentanoic Acid
CAS No.	104531-21-7
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2R,3S)-2-Amino-3-hydroxypentanoic acid; D-three-2-Amino-3-hydroxypentanoic acid; (2R,3S)-3-Hydroxy-2-aminopentanoic acid; 2-Amino-3-hydroxypentanoic acid (2R,3S)-isomer; β-Hydroxy-norvaline (specific isomer); AHP; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (2R,3S)-2-Amino-3-Hydroxy-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.