Description

4-Bromo-2-Fluoro-5-(Trifluoromethyl)Aniline is a high-value, multi-functional aromatic amine building block distinguished by its unique halogen and trifluoromethyl substitution pattern. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling the fine-tuning of their physical, chemical, and biological activities. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance bioavailability and environmental stability.
• Material Science: Serves as a precursor for functional dyes, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Research: Employed in academic and industrial laboratories for cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) to create complex molecular architectures.
• Fluorinated Compound Library: An essential building block for constructing diverse fluorinated compound libraries for high-throughput screening in drug and agrochemical discovery.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-(Trifluoromethyl)Aniline
CAS No.	104460-70-0
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	2-Fluoro-4-bromo-5-(trifluoromethyl)aniline; 5-Amino-2-bromo-4-fluorobenzotrifluoride; 4-Bromo-2-fluoro-5-(trifluoromethyl)benzenamine; 2-Bromo-5-amino-4-fluorobenzotrifluoride; Benzenamine, 4-bromo-2-fluoro-5-(trifluoromethyl)-; 4-Bromo-2-fluoro-alpha,alpha,α-trifluoro-m-toluidine
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Fluoro-5-(Trifluoromethyl)Aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.