Description

4H-Pyrrolo[3,2-D]Pyrimidin-4-One,1,5-Dihydro-7-(Hydroxymethyl)-(9Ci) is a high-purity heterocyclic organic compound, identified by CAS number 104303-72-2, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique fused pyrrolopyrimidine scaffold, which is a privileged structure for developing bioactive molecules with targeted therapeutic effects. This compound is essential for research and development chemists in the pharmaceutical and biotechnology industries, particularly those focused on kinase inhibitor discovery, oncology research, and the synthesis of novel nucleoside analogs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potent kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Oncology Research: Used in the discovery and development of novel anti-cancer agents due to its structural similarity to purine bases and its ability to modulate key enzymatic targets.
• Biochemical Tool Compound: Serves as a core structure for creating probes and assay standards in high-throughput screening and enzymatic studies.
• Nucleoside Analog Synthesis: Acts as a precursor for modified nucleosides with potential antiviral or anticancer activity.
• Agrochemical Research: Explored as an intermediate for developing new herbicides or plant growth regulators leveraging its heterocyclic activity.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Item	Details
Product Name	4H-Pyrrolo[3,2-D]Pyrimidin-4-One,1,5-Dihydro-7-(Hydroxymethyl)-(9Ci)
CAS No.	104303-72-2
Molecular Formula	C7H7N3O2
Molecular Weight	165.15 g/mol
Synonyms	7-(Hydroxymethyl)-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one; 1,5-Dihydro-7-(hydroxymethyl)-4H-pyrrolo[3,2-d]pyrimidin-4-one; 7-Hydroxymethyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one; Pyrrolo[3,2-d]pyrimidin-4(1H)-one, 1,5-dihydro-7-(hydroxymethyl)-; 104303-72-2; 7-(Hydroxymethyl)-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one (9CI)
EINECS	Contact for details

Quality Control

Our 4H-Pyrrolo[3,2-D]Pyrimidin-4-One,1,5-Dihydro-7-(Hydroxymethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP-grade research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.