Description

5-Chloro-4-Fluoro-2-Nitroaniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated nitroaniline structure makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aniline motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, where the chloro-fluoro-nitro substitution pattern confers specific biological activity.
• Dye and Pigment Manufacturing: Serves as a foundational component for synthesizing complex azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating novel carbon-nitrogen bonds.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and methodologies in academic and industrial R&D laboratories.

Basic Information

Product Name	5-Chloro-4-Fluoro-2-Nitroaniline
CAS No.	104222-34-6
Molecular Formula	C6H4ClFN2O2
Molecular Weight	190.56 g/mol
Synonyms	2-Nitro-5-chloro-4-fluoroaniline; 4-Fluoro-5-chloro-2-nitroaniline; 5-Chloro-4-fluoro-2-nitrobenzenamine; Benzenamine, 5-chloro-4-fluoro-2-nitro-; 5-Chloro-4-fluoro-2-nitro-phenylamine; 2-Amino-4-chloro-5-fluoronitrobenzene; 104222-34-6 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Fluoro-2-Nitroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.