Description

Pro-Phe-Gly-Lys CAS NO 104180-29-2 is a synthetic tetrapeptide composed of the amino acids Proline, Phenylalanine, Glycine, and Lysine. This sequence is of significant interest in biochemical research and pharmaceutical development for its potential role in modulating biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, drug discovery, and the study of enzyme substrates or inhibitors. The compound's defined structure makes it a valuable building block for creating more complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor binding assays, and metabolic pathway investigations.
• Cosmeceutical Development: Explored for potential bioactive properties in advanced skincare formulations targeting specific skin functions.
• Academic & Institutional Research: Employed in universities and labs for fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.
• Diagnostic Reagent Component: Potentially used in the development of diagnostic kits and assays that require specific peptide sequences.
• Bioconjugation: The lysine residue provides a primary amine group suitable for conjugation with other molecules, such as dyes, tags, or carriers.

Basic Information

Product Name	Pro-Phe-Gly-Lys
CAS No.	104180-29-2
Molecular Formula	C23H34N6O5
Molecular Weight	474.56 g/mol
Synonyms	H-Pro-Phe-Gly-Lys-OH; Proline-Phenylalanine-Glycine-Lysine; L-Prolyl-L-phenylalanylglycyl-L-lysine; Phenylalanine-Glycine-Lysine-Proline; PGK Peptide; Tetrapeptide Pro-Phe-Gly-Lys; 104180-29-2; Pro-Phe-Gly-Lys-OH
EINECS	Contact for details

Quality Control

Our Pro-Phe-Gly-Lys is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and MS for identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.