Description

5-(Chloromethyl)-1-Methylpyrazolo-[1,5-A]Pyrimidin-7(1H)-One is a high-value, heterocyclic organic building block featuring a reactive chloromethyl group. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its fused pyrazolopyrimidine core.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds and probes used in biochemical and cellular assays.
• Material Science Research: Investigated as a monomer or precursor for creating specialized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-(Chloromethyl)-1-Methylpyrazolo-[1,5-A]Pyrimidin-7(1H)-One
CAS No.	104164-03-6
Molecular Formula	C8H8ClN3O
Molecular Weight	197.62 g/mol
Synonyms	5-(Chloromethyl)-1-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one; 1-Methyl-5-(chloromethyl)pyrazolo[1,5-a]pyrimidin-7(1H)-one; 5-Chloromethyl-1-methylpyrazolo[1,5-a]pyrimidin-7-one; 104164-03-6; Pyrazolo[1,5-a]pyrimidin-7(1H)-one, 5-(chloromethyl)-1-methyl-; 1-Methyl-5-chloromethylpyrazolopyrimidin-7-one
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)-1-Methylpyrazolo-[1,5-A]Pyrimidin-7(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storage under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.