Description

Norfloxacin Hydrochloride is a synthetic fluoroquinolone antibacterial agent, widely recognized for its potent and broad-spectrum activity against gram-positive and gram-negative bacteria. Its primary commercial value lies in its critical role as a key pharmaceutical intermediate in the synthesis of finished antibiotic formulations. This compound is essential for manufacturers in the pharmaceutical industry, particularly those producing oral and topical antibacterial medications for human and veterinary use.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of finished Norfloxacin drug products for human and veterinary medicine.
• Antibacterial Formulations: Key raw material for the production of tablets, capsules, and oral suspensions used to treat bacterial infections.
• Veterinary Medicine: Used in the manufacture of antibacterial treatments for livestock and companion animals.
• Research & Development: Serves as a reference standard and active material in pharmacological and microbiological research studies.
• API Manufacturing: Critical component in the production chain for Active Pharmaceutical Ingredient (API) suppliers.

Basic Information

Product Name	Norfloxacin Hydrochloride
CAS No.	104142-93-0
Molecular Formula	C16H18FN3O3 • HCl
Molecular Weight	363.79 g/mol
Synonyms	Norfloxacin HCl; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride; AM-715 Hydrochloride; MK-0366 Hydrochloride; Lexinor; Zoroxin; Noroxin; Floxacin; 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1H-quinoline-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Norfloxacin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) with detailed results for parameters including assay, related substances, residual solvents, and microbiological purity, supporting compliance with ICH guidelines and relevant pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.