Description

α-Methyl-L-Lysine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative of L-lysine, where a methyl group substitutes a hydrogen atom on the alpha carbon. This structural modification makes it a valuable biochemical tool and a critical building block in advanced research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying enzyme mechanisms, metabolic pathways, and as a precursor in peptide synthesis. Our supply ensures consistent quality and reliable availability for global B2B partners.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies, particularly for lysine-specific enzymes like methyltransferases and decarboxylases.
• Metabolic Pathway Analysis: Employed in tracer studies to investigate amino acid metabolism and protein turnover in cellular and animal models.
• Peptide Synthesis: Incorporated into custom peptide sequences to study structure-activity relationships (SAR) and develop new bioactive compounds.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	α-Methyl-L-Lysine Hydrochloride
CAS No.	104112-34-7
Molecular Formula	C7H16N2O2 • HCl
Molecular Weight	196.67 g/mol (Free base: 160.22)
Synonyms	(S)-2-Amino-2-methyl-6-aminohexanoic acid hydrochloride; (S)-2-Methyllysine hydrochloride; L-α-Methyllysine HCl; H-α-Me-Lys-OH • HCl; 2-Amino-2-methyl-L-lysine hydrochloride; (2S)-2-Amino-2-methyl-6-aminohexanoic acid hydrochloride; 6-Amino-2-amino-2-methylhexanoic acid hydrochloride (L-form)
EINECS	Contact for details

Quality Control

Our α-Methyl-L-Lysine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support compliance with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.