Description

4-Methoxy-3-(Trifluoromethyl)Aniline Hydrochloride is a high-purity, functionalized aniline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the combination of the electron-donating methoxy group and the electron-withdrawing trifluoromethyl group, making it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-generating layers in organic light-emitting diodes (OLEDs) and display technologies.
• Dye & Pigment Manufacturing: Intermediate for producing high-performance, light-fast azo dyes and complex pigments with specific coloristic properties.
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific characteristics such as altered solubility, thermal stability, or refractive index.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	4-Methoxy-3-(Trifluoromethyl)Aniline Hydrochloride
CAS No.	104044-32-8
Molecular Formula	C9H9F3NO•HCl
Molecular Weight	231.63 g/mol (Free base: 191.17 g/mol)
Synonyms	3-(Trifluoromethyl)-4-methoxyaniline hydrochloride; 4-Methoxy-3-(trifluoromethyl)benzenamine hydrochloride; 4-Amino-2-methoxybenzotrifluoride hydrochloride; 2-Methoxy-α,α,α-trifluoro-p-toluidine hydrochloride; 3-Trifluoromethyl-p-anisidine hydrochloride; 4-Methoxy-3-trifluoromethylphenylamine hydrochloride; Aniline, 4-methoxy-3-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-(Trifluoromethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.