Description

6-Fluoro-[1,1'-Biphenyl]-3-Amine is a high-purity fluorinated biphenyl amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique structure, which combines a biphenyl core with fluorine and amine functional groups, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for electron-transport materials and charge-transporting compounds in electronic displays and lighting.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and optical properties.
• Organic Light-Emitting Diodes (OLEDs): Utilized in the synthesis of host or dopant materials for efficient electroluminescent devices.
• Academic & R&D: A valuable reagent for methodological studies in cross-coupling reactions and fluorine chemistry within university and corporate research laboratories.

Basic Information

Product Name	6-Fluoro-[1,1'-Biphenyl]-3-Amine
CAS No.	103977-88-4
Molecular Formula	C12H10FN
Molecular Weight	187.21 g/mol
Synonyms	3-Amino-6-fluorobiphenyl; 6-Fluoro-3-biphenylamine; 6-Fluorobiphenyl-3-amine; 3'-Amino-6-fluorobiphenyl; 2-Fluoro-5-phenylaniline; 5-(2-Fluorophenyl)aniline; Biphenyl-3-amine, 6-fluoro-; 103977-88-4
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-[1,1'-Biphenyl]-3-Amine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling should be conducted under subdued light or in amber glass containers to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.