Description

n-Acetyl-S-(n-Methylcarbamoyl)-L-Cysteine is a specialized cysteine derivative with a unique carbamoyl-protected thiol group. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or reference standard in the synthesis of novel drug candidates and biochemical probes. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on areas such as prodrug design, enzyme inhibition studies, and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Biochemical Research: Used as a reference standard or reagent in studies involving cysteine metabolism, enzyme mechanisms, and protein modification.
• Prodrug Development: Its protected thiol structure makes it a valuable precursor in designing prodrugs that require controlled release of thiol-containing active moieties.
• Peptide Synthesis: Employed as a modified cysteine residue in the solid-phase or solution-phase synthesis of specialized peptides and peptide mimetics.
• Metabolite Standard: Acts as a certified reference material (CRM) in analytical laboratories for the quantification of related metabolites in biological samples via LC-MS or HPLC.
• Chemical Biology Tool: Utilized in the development of activity-based probes (ABPs) or affinity labels for studying thiol-reactive enzymes and proteins.

Basic Information

Product Name	n-Acetyl-S-(n-Methylcarbamoyl)-L-Cysteine
CAS No.	103974-29-4
Molecular Formula	C7H12N2O4S
Molecular Weight	220.25 g/mol
Synonyms	N-Acetyl-S-(N-methylcarbamoyl)cysteine; N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine; L-Cysteine, N-acetyl-S-(N-methylcarbamoyl)-; Acetyl-S-(methylcarbamoyl)cysteine; S-(N-Methylcarbamoyl)-N-acetyl-L-cysteine; N-Acetyl-S-(methylaminocarbonyl)-L-cysteine; (2R)-2-Acetamido-3-[(methylcarbamoyl)sulfanyl]propanoic acid
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(n-Methylcarbamoyl)-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.