Description

H-Gly-Gly-Asp-Ala-Oh CAS NO 103972-83-4 is a high-purity tetrapeptide sequence, Glycyl-Glycyl-Aspartyl-Alanine, designed for advanced research and development applications. This compound serves as a critical building block and model substrate in biochemical studies, particularly for investigating enzyme specificity and protein-protein interactions. It is essential for pharmaceutical researchers, biochemists, and peptide synthesis specialists working in drug discovery, proteomics, and diagnostic assay development.

Application

• Biochemical Research: Used as a specific substrate for studying the activity and kinetics of proteolytic enzymes like caspases and other aspartic acid-specific proteases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and quality control of novel therapeutic peptides and peptidomimetics.
• Proteomics & Diagnostics: Employed in the development of enzyme-linked immunosorbent assays (ELISA) and other diagnostic kits to detect and quantify specific protease activities.
• Cell Biology Studies: Utilized in research focused on apoptosis (programmed cell death) and other cellular signaling pathways where specific peptide cleavage is a marker.
• Peptide Library Construction: Acts as a fundamental component in the synthesis of combinatorial peptide libraries for high-throughput screening.
• Academic & Institutional Research: Provides a well-defined peptide sequence for teaching and fundamental research in university and institutional laboratories.

Basic Information

Product Name	H-Gly-Gly-Asp-Ala-Oh
CAS No.	103972-83-4
Molecular Formula	C13H21N5O8
Molecular Weight	375.34 g/mol
Synonyms	Glycyl-glycyl-L-aspartyl-L-alanine; GGDPA; H-Gly-Gly-Asp-Ala-OH; Tetrapeptide GGDPA; L-Alanine, L-aspartylglycylglycyl-; Aspartylalanylglycylglycine; GGDPA peptide; CAS 103972-83-4
EINECS	Contact for details

Quality Control

Every batch of H-Gly-Gly-Asp-Ala-Oh is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.