Description

1-Propanone, 2,2-Dimethyl-1-(5-Pyrimidinyl)- (9Ci) is a specialized organic compound featuring a pyrimidine ring, a key heterocyclic scaffold in medicinal chemistry. This CAS 103686-53-9 material serves as a crucial advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily required by research institutions and pharmaceutical development teams focused on creating new therapeutic agents, particularly in antiviral and anticancer domains.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific enzymes or receptors.
• Antiviral Drug Research: Used in the development of pyrimidine-based nucleoside analogs and other antiviral compounds.
• Oncology Research: Serves as a precursor for kinase inhibitors and other targeted cancer therapies.
• Agrochemical Development: Potential intermediate for creating new herbicides or fungicides with pyrimidine cores.
• Material Science: Can be utilized in the synthesis of specialty polymers or ligands for metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university labs and CROs for method development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-Propanone, 2,2-Dimethyl-1-(5-Pyrimidinyl)- (9Ci)
CAS No.	103686-53-9
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	2,2-Dimethyl-1-(5-pyrimidinyl)-1-propanone; 1-(Pyrimidin-5-yl)-2,2-dimethylpropan-1-one; 5-Acetylpyrimidine, 2,2-dimethyl derivative; 5-(2,2-Dimethylpropionyl)pyrimidine; 5-Pyrimidinyl tert-butyl ketone; tert-Butyl 5-pyrimidinyl ketone; 103686-53-9 (CAS)
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency for research and development purposes. Certificates of Analysis (COA) detailing purity (typically by HPLC or GC), identity confirmation (by IR, NMR, and/or MS), and impurity profiles are provided with every shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.