Description

3'-Azido-N6-Benzoyl-3'-Deoxyadenosine is a chemically modified nucleoside analog, a key building block in the synthesis of oligonucleotides and other bioactive molecules. Its primary value lies in its azido functional group, which enables efficient "click chemistry" reactions for bioconjugation and labeling applications. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic probe synthesis, where precise chemical modification is required.

Application

• Oligonucleotide Synthesis: A critical phosphoramidite precursor for introducing modified bases into DNA/RNA strands.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation.
• Antiviral & Anticancer Research: Serves as a scaffold for developing nucleoside-based prodrugs and therapeutic agents.
• Diagnostic Probe Development: Used to create labeled probes for fluorescence in situ hybridization (FISH) and other detection systems.
• Chemical Biology Studies: Enables site-specific labeling and cross-linking of biomolecules for mechanistic studies.
• Polymerase Substrate: Investigated as a substrate or inhibitor for specialized DNA polymerases.

Basic Information

Product Name	3'-Azido-N6-Benzoyl-3'-Deoxyadenosine
CAS No.	103597-10-0
Molecular Formula	C17H16N8O3
Molecular Weight	380.36 g/mol
Synonyms	3'-Azido-3'-deoxy-N6-benzoyladenosine; 3'-Azido-N6-Bz-3'-dA; 3'-N3-N6-Bz-3'-dA; 3'-Azido-N6-benzoyl-2'-deoxyadenosine; 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine; 3'-Azido-N6-Bz-dA; 3'-Azido-N6-benzoyl-3'-deoxy-adenosine; 3'-Azido-N6-benzoyl-2'-deoxy-adenosine
EINECS	Contact for details

Quality Control

Our 3'-Azido-N6-Benzoyl-3'-Deoxyadenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.