Description

Chenodeoxycholyltyrosine is a synthetic bile acid derivative, specifically a conjugate of chenodeoxycholic acid and the amino acid tyrosine. This compound is of significant interest in pharmaceutical research and development due to its role as a key intermediate and reference standard. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic manufacturers engaged in metabolic studies, drug discovery, and the development of therapeutic agents targeting liver and gastrointestinal disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents, particularly those targeting bile acid receptors like FXR and TGR5.
• Biochemical Research: Used as a reference standard and probe in metabolic pathway studies, enzyme kinetics, and investigations into bile acid transport and signaling.
• Diagnostic Development: Employed in the development and calibration of diagnostic assays and kits for measuring bile acid profiles in clinical samples.
• Reference Material: Provides a high-purity standard for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Academic Research: Facilitates studies in hepatology, gastroenterology, and metabolic disease research within university and institutional labs.

Basic Information

Product Name	Chenodeoxycholyltyrosine
CAS No.	103528-65-0
Molecular Formula	C32H47NO6
Molecular Weight	541.73 g/mol
Synonyms	N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]-L-tyrosine; Chenodeoxycholic Acid Tyrosine Amide; CDCA-Tyr; Tyrosinechenodeoxycholic Acid; 3α,7α-Dihydroxy-5β-cholan-24-oyl-L-tyrosine; Chenodeoxycholyl-L-tyrosine; L-Tyrosine, N-[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]-
EINECS	Contact for details

Quality Control

Our Chenodeoxycholyltyrosine CAS NO 103528-65-0 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and mass spectrometry. The product is suitable for use as a pharmaceutical reference standard and research-grade biochemical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.