Description

Acth (5-8) CAS NO 103470-78-6 is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), specifically encompassing amino acid residues 5 through 8. This compound is a critical intermediate and reference standard in pharmaceutical research and development, particularly for studying the structure-activity relationships of ACTH and related neuropeptides. It is essential for researchers and manufacturers in the fields of endocrinology, neuroscience, and peptide-based therapeutic discovery.

Application

• Pharmaceutical Research: As a key intermediate in the synthesis and study of full-length ACTH and its analogs.
• Biochemical Standard: Used as a reference standard in analytical methods like HPLC and mass spectrometry for quality control of peptide products.
• Neuroscience Studies: Employed in research to investigate the role of specific ACTH sequences in brain function and behavior.
• Drug Discovery: Serves as a building block for developing novel peptide-based diagnostics and therapeutics targeting the melanocortin system.
• Academic & Institutional Labs: Utilized in university and research institute settings for fundamental studies in endocrinology and peptide chemistry.

Basic Information

Product Name	Acth (5-8)
CAS No.	103470-78-6
Molecular Formula	C22H34N8O7
Molecular Weight	522.56 g/mol
Synonyms	ACTH (5-8); Adrenocorticotropic Hormone (5-8); H-Met-Glu-His-Phe-OH; ACTH Fragment 5-8; Tetrapeptide H-Met-Glu-His-Phe; L-Methionyl-L-α-glutamyl-L-histidyl-L-phenylalanine; Melanotropin (5-8)
EINECS	Contact for details

Quality Control

Our Acth (5-8) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content (AAA)	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.