Description

2,2,3,3-Tetrafluoro-6-Hydroxybenzodioxene is a high-purity, fluorinated benzodioxene derivative of significant interest in advanced chemical synthesis. This compound matters for its role as a key synthetic intermediate and building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, specialty polymers, and advanced materials where the introduction of fluorine atoms is critical for modulating biological activity, stability, and material properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorinated benzodioxene core enhances metabolic stability and bioavailability.
• Advanced Material Precursor: Acts as a monomer or functional additive in the production of specialty polymers, coatings, and electronic materials requiring high thermal and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel ligands that can modulate catalytic activity in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and developing new fluorination methodologies in academic and industrial R&D settings.

Basic Information

Product Name	2,2,3,3-Tetrafluoro-6-Hydroxybenzodioxene
CAS No.	103467-50-1
Molecular Formula	C8H2F4O3
Molecular Weight	222.10 g/mol
Synonyms	6-Hydroxy-2,2,3,3-tetrafluoro-1,4-benzodioxene; 2,2,3,3-Tetrafluoro-1,4-benzodioxin-6-ol; Tetrafluorohydroxybenzodioxene; 1,4-Benzodioxin-6-ol, 2,2,3,3-tetrafluoro-; 103467-50-1 (CAS Name); TFBDO (abbreviation); Fluorinated benzodioxene alcohol
EINECS	Contact for details

Quality Control

Our 2,2,3,3-Tetrafluoro-6-Hydroxybenzodioxene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.