Description

H-Arg-Gly-Val-Phe-Arg-Oh is a synthetic hexapeptide with the sequence Arginine-Glycine-Valine-Phenylalanine-Arginine. This compound, identified by CAS NO 103424-98-2, is a valuable research-grade biochemical tool used in the study of peptide structure, function, and interactions. It serves as a critical intermediate and reference standard for pharmaceutical research, particularly in the development of enzyme inhibitors and receptor ligands. Industries requiring high-purity peptide building blocks for life science research and diagnostic development are the primary users of this material.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and proteomics research.
• Pharmaceutical Development: Serves as a key intermediate or a lead compound in the discovery and synthesis of novel therapeutic peptides.
• Protease/Enzyme Inhibition Studies: Employed to investigate the specificity and mechanism of action of various proteases due to its specific amino acid sequence.
• Cell Biology & Signal Transduction: Utilized in research focused on peptide-mediated cell signaling pathways and receptor binding assays.
• Diagnostic Reagent Manufacturing: Acts as a critical component in the development of immunoassays and other diagnostic test kits.
• Academic Research: Provides a model peptide for teaching and advanced research in universities and institutional labs focusing on peptide chemistry and molecular biology.

Basic Information

Product Name	H-Arg-Gly-Val-Phe-Arg-Oh
CAS No.	103424-98-2
Molecular Formula	C32H53N13O6
Molecular Weight	715.86 g/mol
Synonyms	Arg-Gly-Val-Phe-Arg; RGVFR; H-Arg-Gly-Val-Phe-Arg-OH; Hexapeptide RGVFR; L-Arginyl-glycyl-L-valyl-L-phenylalanyl-L-arginine; Pentapeptide RGVFR (common misnomer); Peptide Sequence 78-83 (context-dependent); Research Peptide 103424-98-2
EINECS	Contact for details

Quality Control

Our H-Arg-Gly-Val-Phe-Arg-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA) to ensure sequence integrity and correct composition. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.